“I cannot take statins the pain is too much to bear”


“I cannot take statins the pain is too much to bear.”

This comment was left by one of our regular readers, called Paul… and sadly, the unbearable muscle pain Paul talks about is one of the most common and most debilitating side effects associated with cholesterol-lowering statin drugs.

If you think that you have to live with the side effects of this drug in order to gain the supposed heart health benefits of lowering your cholesterol, then this article is for you.

No pain, no gain?

Doctors are quick to dismiss the muscle pain, weakness and fatigue experienced by their patients who are taking statin drugs.

But don’t allow your doctor to fob you off.

Those cramps and knife-sharp pangs shooting down your legs, waking you up in the middle of the night… or the muscle weakness and fatigue you experience when you try to climb the stairs are all signs that your muscles are beginning to waste away — slowly being damaged to the point of no repair.

You see statins work by inhibiting an enzyme known as HMG-coA reductase. This enzyme is responsible for the manufacturing of cholesterol in the liver as well as the production of the nutrient-powerhouse and essential building block coenzyme Q10 (CoQ10).

CoQ10 is a major player in the production of ‘adenosine triphosphate’ (ATP). ATP is what gives energy to every cell throughout your entire body. If your cells don’t produce CoQ10, there can be no ATP, and without ATP you will have no energy. In addition, your body will be unable to synthesise protein — the building block of your muscles… As a result muscle pain, weakness and fatigue starts to set in and before you know it climbing a flight of stairs will have you exhausted by the mere thought of it.

In a 2013 study, published in the Journal of the American College of Cardiology (JACC), Danish researchers measured CoQ10 levels in individuals taking simvastatin (a commonly-prescribed statin), and compared them with individuals not taking statins. The results showed that patients taking statins had significantly lower levels of CoQ10.

The researchers concluded: “It is plausible that our finding partly explains the muscle pain and exercise intolerance that many patients experience with their statin treatment.”

But here’s the real kicker:

The heart is a muscle, and depleting it of CoQ10 may be hazardous for cardiovascular health as it may weaken the heart and lead to what is known as ‘heart failure’. In fact, one of the most common and thoroughly researched uses of CoQ10 is that it helps protect the heart and blood vessels from the damaging effects of oxidative stress (also called free radical damage).

So, by taking a statin drug you might be reducing your cholesterol, but it will also deplete your body of an essential enzyme that in fact PROTECTS your heart.

Disclaimer: Bear in mind the material contained in this article is provided for information purposes only. We are not addressing anyone’s personal situation. Please consult with your own physician before acting on any recommendations contained herein.


Larsen S, et al. Simvastatin Effects on Skeletal Muscle – Relation to Decreased Mitochondrial Function and Glucose Intolerance. J Am Coll Cardiol. 2013;61(1):44-53

Annals of Internal Medicine October 3, 2006; 145(7): 520-530

Coenzyme Q10 Supplementation Decreases Statin-Related Mild-to-Moderate Muscle Symptoms: A Randomized Clinical Study, medscimonit.com

Hoffman KB, et al. A Survey of the FDA’s AERS Database Regarding Muscle and Tendon Adverse Events Linked to the Statin Drug Class. PLoS One. 2012;7(8):e42866. Epub 2012 Aug 22.

Statins cause the disease it seeks to cure – Shock research warns drug hardens arteries, published online 10.01.16, sott.net

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  • It took me years to convince my dad to come off these drugs. His cholesterol was slightly higher than normal what is considered and just because of his age his doctor insisted that he took these drugs. We have no family history of heart disease and it was astounding to see how, within less than a month after he began to take statins, his health started going down hill. Fortunately he eventually listened to me and it looks like he is slowly but surely recovering. It’s horrible to think that these drugs are prescribed to millions of people.

  • These drugs are poison. I took statins for three months and watched my health fall apart. Liver dysfunction, muscle pain, fatigue, headaches, blood sugar problems and a constant bleeding nose. These are not any problems I’ve every had. And the worst is, my cholesterol was not even that high but my doctor scared me into taking them. I regret doing it.

  • I had same problem having tried every type of statin manufactured. This started the sleep problem I still have years later when my muscles go into spasm. I also gained weight then gall bladder had to be removed afte a year of horrendous pain. Then told I had an enlarged fatty liver which the surgeon caught whilst removing the gallbladder resulting in me being taken to Kings college Liver Intensive Care due to large loss of blood. It has taken me a whole year to get over this with a 22cms cut after laparoscopic surgery failed. I think I am lucky to be alive.
    No more will I do as I am told I would rather be dead. Sandra

    • Dear Sandra,

      Thank you for sharing your experience and we are so sorry to hear about the damage you suffered to your health. We wish you a speedy recovery and hope that you find a good and caring alternative health specialist that will help you get your health back on track.

  • I took these drugs for two days and the pain in my legs nearly sent me over the edge. This stuff is poison.

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