Why is it that some people seem to stay ‘forever young’, while others look and feel old before their time? Certainly, diet and lifestyle have a lot to do with it, but around 10 years ago, researchers made a breakthrough discovery that completely changed the way they viewed ageing and longevity.
The discovery involved telomeres. These short regions at the ends of chromosomes (the thread-like structures in body cells that carry our genes) have an important function in protecting our genetic material every time a cell divides. But, with each cell division a little bit of the telomeres is lost – and, when they become too short to protect the chromosomes, cell division is no longer possible and the cell ages and dies.
Longer telomeres mean slower ageing and a potentially longer life. Shorter telomeres are not only associated with faster ageing but with disease too. They have been linked with several chronic conditions, including hypertension, cardiovascular disease, insulin resistance, type 2 diabetes, depression, osteoporosis, and obesity.1
Anything that protects telomere length could help prevent the health problems commonly associated with ageing. Recently, research has revealed that some herbs and nutrients have that amazing ability – and we are delighted to rush JNHS readers the news that a combination of the best of them is now available in the UK as Enzymedica Telomere Plus.
Telomere Plus contains a proprietary blend of astragalus root, rhodiola root and broccoli seed extract, together with 500 IU of vitamin D3. These active ingredients have been found to activate production in the body of an enzyme called telomerase, which prevents the shortening of telomeres during cell division and may even make them longer.
All body cells have the ability to make telomerase, but in practice most don’t. Only the kinds of cells that have to be constantly dividing, like stem cells, white blood cells and sperm cells, produce significant amounts. The telomerase activators contained in Enzymedica Telomere Plus could boost the production of this remarkable enzyme in every cell of your body.
The 4 fantastic ingredients in Telomere Plus win hands down in laboratory tests
Scientists at the Roskamp Institute, in Sarasota, Florida, recently tested the telomerase activation properties of 14 individual natural compounds and eight blends of these compounds. They discovered that astragalus root, rhodiola root, broccoli seed extract and vitamin D3 all had particularly strong telomerase-boosting activity, when tested as individual compounds.2
What is more, when combined together, this four-ingredient blend outperformed all others tested. You can now benefit from exactly the same combination of natural ingredients in Telomere Plus. And, in addition to maintaining telomere length, these incredible compounds help combat ageing and boost your health in a host of other ways, too.
In traditional Chinese medicine, astragalus root is considered a vital herbal tonic that stimulates the immune system and promotes health and longevity. One of the many active ingredients in astragalus is cycloastragenol, a compound now shown to be a potent telomerase activator that can increase telomere length.3 Animal studies suggest that, in brain cells, this property of cycloastragenol could help prevent depression, cognitive decline and psychiatric disorders.
Astragalus has a wide range of other health benefits, too. In particular, it is antioxidant, anti-inflammatory, helps to control blood-sugar levels, protects the liver from damage and may protect against cancer, too.4 Clinical trials have shown that astragalus root extract is one of the most effective natural compounds for both type 1 and type 2 diabetes.5
For more than a decade, researchers at the University of California have studied the impact of the herb Rhodiola rosea on ageing and longevity. They have discovered that it delays cell ageing and extends the lifespan of fruit flies by 25 per cent.6 Rhodiola contains at least 140 different bioactive compounds and one of these, salidroside, has been shown to protect and repair DNA, the molecule that carries genetic information.7 Together with rhodiola’s ability to activate the enzyme telomerase, this DNA repair effect supports healthy cell division and helps delay cell ageing.
Rhodiola also combats the adverse effects of ageing via the immune system. As we age, our immune function declines in a process known as immune senescence, leaving us more susceptible to infections, autoimmune diseases and cancer. Studies show that rhodiola compounds help to prevent immune senescence, in part by increasing the lifespan of immune cells called T-lymphocytes.8
These incredible natural compounds could keep every cell in your body young and healthy
The broccoli seed extract included in Telomere Plus has been widely studied for its anti-cancer properties – and new research shows it has amazing anti-ageing effects, too. Broccoli seeds are bursting with beneficial compounds, including one called NMN (nicotinamide mononucleotide). NMN boosts production of a vital coenzyme, NAD, declining levels of which are a key driver of the ageing process.
When scientists at Washington University School of Medicine fed NMN to healthy mice, they found it suppressed age-associated body weight gain, enhanced energy metabolism, promoted physical activity, improved insulin sensitivity and blood-fat levels, and prevented eye problems and other disease conditions.9
The final ingredient in the formula, Vitamin D3, supports just about every aspect of physical and mental health, and also plays a critical role in the way we age. The ageing process involves several important changes in cell biology, including telomere shortening, DNA disorders, inflammation, free radical damage, dysfunction of the mitochondria (energy centres), and alterations in gene expression and cell signalling pathways. Remarkably, every single one of these changes is regulated by vitamin D3. Adequate levels of the vitamin keep them under control, but a deficiency (widespread in the UK) allows them to accelerate and trigger the onset of age-related illnesses.10
What to take for best results
The recommended dose of Enzymedica Telomere Plus is one capsule daily, with or without food.
If you’re pregnant or breastfeeding, or if you are being treated for any medical condition, you are advised to talk to your doctor before taking this supplement.
Disclaimer: This article is part of the Agora Health's extensive research archive. The research and information contained in this article was accurate at the the time of publication but may have been updated since the date of publication. Full references and citations for this article are available in the downloadable PDF version of the monthly The Journal of Natural Health Solutions issue in which this article appears.
Bear in mind the material provided in this content is for information purposes only. We are not addressing anyone’s personal situation. Please consult with your own physician before acting on any recommendations contained herein.
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